About Free Semaglutide Calculator

Our Mission

To democratize access to evidence-based weight loss projection tools, empowering individuals researching GLP-1 medications with accurate, transparent, and clinically-backed information to set realistic expectations for their weight loss journey.

What We Do

The Free Semaglutide Calculator is a free, evidence-based tool that provides personalized weight loss projections for individuals considering or currently using GLP-1 receptor agonist medications such as:

Our calculator generates week-by-week weight loss timelines, BMI changes, and personalized protein intake recommendations to help users preserve muscle mass during their weight loss journey.

How the Calculator Works

Unlike generic weight loss calculators that use outdated formulas or unsubstantiated estimates, our tool is built on peer-reviewed clinical trial data from the most rigorous studies conducted on GLP-1 medications:

16.9%
Average weight loss
Wegovy (STEP-1)
10.5%
Average weight loss
Ozempic (SUSTAIN)
22.5%
Average weight loss
Mounjaro (SURMOUNT-1)

Calculation Methodology

Our algorithm works as follows:

  1. Medication Selection: You select the specific GLP-1 medication you are using or considering. Each medication has distinct average weight loss percentages based on clinical trials.
  2. Weight Loss Percentage Application: The calculator applies the clinically-proven weight loss percentage for your selected medication (e.g., 16.9% for Wegovy, 22.5% for Mounjaro).
  3. Timeline Generation: We generate a week-by-week projection using a logarithmic curve that mirrors real-world weight loss patterns — faster loss in the first 6 months, gradual tapering toward months 9-12.
  4. BMI Calculation: We calculate your current BMI and projected BMI at goal weight using the standard formula: (weight in lbs ÷ height² in inches) × 703.
  5. Protein Recommendation: To help preserve lean muscle mass, we recommend 1 gram of protein per pound of goal body weight, a strategy supported by resistance training research.

Clinical Trial Data Sources

Our projections are based exclusively on data from large-scale, randomized, double-blind, placebo-controlled clinical trials published in leading medical journals:

STEP-1 Trial (Semaglutide 2.4mg — Wegovy)

Study Design: 68-week randomized, double-blind, placebo-controlled trial

Participants: 1,961 adults with obesity (BMI ≥30) or overweight (BMI ≥27) with at least one weight-related comorbidity

Results: Average weight loss of 16.9% of body weight (~37 lbs for a 220 lb individual)

Published: New England Journal of Medicine (2021)

SUSTAIN Trials (Semaglutide 1mg — Ozempic)

Study Design: Series of randomized, double-blind trials evaluating semaglutide for type 2 diabetes management

Participants: Adults with type 2 diabetes

Results: Average weight loss of 10.5% at 1mg weekly dose over 68 weeks

Published: The Lancet and Diabetes Care (2017-2019)

SURMOUNT-1 Trial (Tirzepatide 15mg — Mounjaro/Zepbound)

Study Design: 72-week randomized, double-blind, placebo-controlled trial

Participants: 2,539 adults with obesity or overweight with weight-related conditions (excluding diabetes)

Results: Average weight loss of 22.5% at the 15mg maintenance dose (highest efficacy among GLP-1 medications)

Published: New England Journal of Medicine (2022)

SCALE Trial (Liraglutide 3mg — Saxenda)

Study Design: 56-week randomized, double-blind, placebo-controlled trial

Participants: 3,731 adults with obesity or overweight with at least one comorbidity

Results: Average weight loss of 8.0% at the 3mg daily dose

Published: New England Journal of Medicine (2015)

Understanding GLP-1 Medications

What is Semaglutide?

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that mimics the natural GLP-1 hormone produced in the gut. It works by:

What is Tirzepatide?

Tirzepatide is a dual GIP/GLP-1 receptor agonist, meaning it activates both glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptors. This dual action produces superior weight loss outcomes compared to semaglutide alone.

Why We Built This Tool

GLP-1 medications have transformed the landscape of obesity treatment, but many individuals struggle to find transparent, evidence-based information about what to expect. We created this calculator to:

What We Are NOT

It's important to understand the limitations of our tool:

Our Commitment to Accuracy

We are committed to maintaining the highest standards of scientific accuracy and transparency:

Future Development

We are continuously working to improve the calculator by:

Contact Us

We welcome feedback, questions, and suggestions for improving the Free Semaglutide Calculator. Please reach out to us at:

Email: contact@freesemaglutidecalculator.com