See real monthly costs for Wegovy, Ozempic, Mounjaro, Zepbound, Saxenda, and compound semaglutide — retail, with insurance, and projected over 12 months.
Price Disclaimer
Prices are approximate national averages as of early 2026 and vary by pharmacy, region, insurance plan, and eligibility. Verify actual costs with your pharmacy and insurer before starting treatment.
Choose one or more medications to see their cost breakdown below.
Cumulative cost over one year at retail price (solid lines) and estimated insurance copay (dashed lines). Compound semaglutide shown at average $300/month.
| Medication | Retail / Month | With Insurance | Compound Option | Annual (Retail) | Annual (Insurance) |
|---|---|---|---|---|---|
| Wegovy Semaglutide 2.4mg |
~$1,350 | ~$200–$500 | N/A (brand only) | ~$16,200 | ~$2,400–$6,000 |
| Ozempic Semaglutide 1mg |
~$900 | ~$25–$200 T2D | N/A (brand only) | ~$10,800 | ~$300–$2,400 |
| Mounjaro Tirzepatide 15mg |
~$1,100 | ~$25–$150 T2D | N/A (brand only) | ~$13,200 | ~$300–$1,800 |
| Zepbound Tirzepatide 15mg |
~$1,060 | ~$25–$150 Limited | N/A (brand only) | ~$12,720 | ~$300–$1,800 |
| Saxenda Liraglutide 3mg |
~$1,500 | ~$200–$400 Varies | N/A (brand only) | ~$18,000 | ~$2,400–$4,800 |
| Compound Semaglutide Licensed compounding pharmacies |
~$200–$400 | Not covered | IS compound | ~$2,400–$4,800 | ~$2,400–$4,800 (cash only) |
Insurance coverage is the single biggest factor in your out-of-pocket cost. Here's how coverage typically works for each medication in 2026:
Both Ozempic and Mounjaro are FDA-approved for type 2 diabetes. If you have a T2D diagnosis, most commercial insurance plans cover them generously — often $25–$150/month copay. Without a diabetes diagnosis, coverage drops sharply or disappears entirely.
Wegovy and Zepbound are approved specifically for chronic weight management. Coverage is improving but inconsistent — many employer-sponsored plans still exclude weight loss medications. Medicare Part D now covers Wegovy for cardiovascular risk reduction following the SELECT trial. Check your plan's formulary specifically.
Insurers with known Wegovy/Zepbound coverage: Cigna, Aetna, some BCBS plans, United Healthcare (plan-dependent), and Medicare Part D (with qualifying indication). Always verify directly with your insurer before filling.
| Insurer | Wegovy Coverage | Zepbound Coverage | Notes |
|---|---|---|---|
| Medicare Part D | Yes (CV indication) | Varies by plan | Post-SELECT trial; BMI criteria apply |
| Cigna | Yes (most plans) | Yes (most plans) | Prior auth required; BMI + comorbidity criteria |
| Aetna | Yes (many plans) | Yes (many plans) | Prior auth, BMI ≥30 or ≥27 + comorbidity |
| BCBS | Varies by plan | Varies by plan | Highly plan-dependent; check your specific plan |
| United Healthcare | Plan-dependent | Plan-dependent | Many commercial plans exclude; check formulary |
| Medicaid | State-dependent | State-dependent | Some states (CA, NY) now cover; most still don't |
Novo Nordisk offers a Wegovy savings card that can reduce cost to as low as $0/month for eligible commercially insured patients and ~$650/month for uninsured patients. Eli Lilly offers similar programs for Mounjaro and Zepbound. Search "[medication name] savings card" on the manufacturer's official website.
Both Novo Nordisk and Eli Lilly offer PAPs for patients who are uninsured or underinsured and meet income criteria. These can provide medication at no cost or very low cost. Ask your prescriber or visit the manufacturer's website directly.
Licensed compounding pharmacies (503A and 503B facilities) can produce semaglutide at $200–$400/month. While not FDA-approved, these are a common lower-cost option accessed through telehealth platforms like Hims/Hers and Henry Meds. Note: the FDA has warned that compounded semaglutide availability may decline as supply normalizes. See our telehealth guide for platform options.
GoodRx and similar discount programs can reduce the retail price at participating pharmacies. Cost Plus Drugs (costplusdrugs.com) has worked to add semaglutide to their formulary. Compare prices across pharmacies — they can vary by $100–$200/month for the same medication.
If your insurer denies coverage, your prescriber can often submit a prior authorization with documentation of medical necessity. Many denials are overturned on appeal, especially with comorbidities (hypertension, sleep apnea, prediabetes, or cardiovascular disease). Ask your doctor to write a detailed letter of medical necessity.
If you have or are at risk for type 2 diabetes, your provider may be able to prescribe Ozempic or Mounjaro under the T2D indication, which has much better insurance coverage than the obesity indication. This is a legitimate clinical pathway when appropriate — discuss with your doctor.
Use our free calculator to see how much weight you could lose on any of these medications, projected week by week based on clinical trial data.
Calculate Your Projected Weight Loss →Prices shown are approximate national averages and vary by pharmacy, region, insurance plan, and eligibility. Always verify costs with your pharmacy and insurance provider. This page does not constitute financial or medical advice.
© 2026 Free Semaglutide Calculator. Evidence-based weight loss projections.